How can weight be managed by taking Orlistat?

You can manage your weight by changing your diet, exercising, or taking medications. Lifestyle changes are generally the most beneficial management behaviors because they can help you maintain long-term weight loss and keep excess weight off. It is important to eat more healthful foods, Women should consume no more than 1,500 calories per day and men no more than 1,800 calories per day. There is one FDA-approved over-the counter (OTC) weight-loss product, orlistat, that can be helpful when used together with a reduced-calorie diet.
Orlistat (brand name: alli) is an FDA-approved OTC medication that can help overweight adults lose weight. Orlistat works by blocking fat from being absorbed into the body after it is eaten during a meal. Approximately 5 to 10 pounds may be lost during the first 6 months of orlistat use.
One orlistat capsule is taken with a meal, or within 1 hour of each meal containing fat, three times per day (breakfast, lunch, and dinner). If you skip a meal, do not take orlistat. No more than three capsules of orlistat should be taken in a single day. A multivitamin is recommended when orlistat is used, but it should be taken at least 2 hours after orlistat or at bedtime. Continue to be physically active and control your diet during and after taking orlistat to help maintain the weight loss.

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2. "FDA Approves alli (orlistat 60 mg capsules) Over-The-Counter" (PDF) (Press release). PRNewswire. 7 February 2007. Archived from the original (PDF) on 24 August 2007. Retrieved 8 April 2007.
3. From page 12 of the Alli Companion Guide, 2007 edition: "They can be an incentive to keep from eating more fat than you really intend to."
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